运用仿生纤维引导组织再生的机遇

主题:    运用仿生纤维引导组织再生的机遇主讲人:   Hongjun Wang地点:   松江校区纺织学院3004室时间:   2017-06-17 09:30:00组织单位:   纺织学院

报告人简介:

Hongjun Wang,Associate Professor of Biomedical Engineering,Associate  Professor of Chemistry, Associate Professor of Chemical Biology,Stevens  Institute of Technology, New Jersey, US. His research interests includecomplex  tissue formation, 3D in vitro tissue model, biomimetic materialsdesign,  cell-materials interaction, nanomedicine, and regenerative medicine. Heobtained  the 1st Ph.D. in Polymer Chemistry and Physics (Biomaterials) in 1998from Nankai  University and University of Twente, Enschede, the Netherland, andthe 2nd Ph.D.  in Biomedical Engineering (Tissue Engineering) in 2003 from HarvardMedical  School and Massachusetts General Hospital, Boston. He was working asthe research  fellow from 2003 to 2005. Out of 70 peer-reviewed journalpublications in  addition to 5 pending patents, 2 issued patents, 7 provisionalpatents, 2  editorial papers, 8 book chapters, 1 book, over 100 conferenceabstracts &  proceedings and invited talks since 1994.


报告摘要:

After decades of efforts from both academic andindustrial researchers, a  great mass of knowledge and tremendous progress hasbeen made in tissue  engineering, which has great potential in both regenerativemedicine and as an in  vitro testing platform.However, in creation of large tissues/organs with  multiplefunctionalities and hierarchical structures, several challenges,  e.g.,vascularization and spatially controlled cell organization confound  currenttissue engineering strategy.Recognitionof these challenges inspires our  ongoing efforts in creating vasculature intissue-engineered substitutes and the  development of bottom-up tissueengineering. The former enables the free exchange  of nutrient and gas acrossthe large substitutes, and the latter allows  straightforward manipulation ofthe spatial arrangement of multiple cell types  and customization of the growthenvironment for individual cell type. Along with  this endeavor, theconfiguration of a cell-friendly microenvironment is critical  to guarantee thedesirable cell phenotype, leading to functional tissue  formation. In thisregard, a biomimetic approach is taken in biomaterial design  to maximallyrecapture the native cell-residing environment on a  micro/nanoscale.


报告语言:双语  

撰写: 刘秀琴信息员:郭珊珊编辑:向娟