主讲人简介：Prof. CC Chengraduated from University of Massachusetts Lowell, US, with a Ph.D. in thepolymer sciences and engineering. Prof. CC Chen joined Taipei MedicalUniversity as a faculty member of Graduate Institute of Biomedical Materialsand Tissue Engineering, College of Biomedical Engineering since 2003. Hisversatile research background covers from chemical (BA, Chung-Yuan ChristianUniversity, Taiwan), textile (MS, Feng-Chia university, Taiwan), polymer andfinally biomedical engineering. At Taipei Medical University, Prof. Chen hasdeveloped a novel hollow fiber substrate of Microtube array membrane (MTAM),via co-axial electrospinning and attention have been paid to the utilization ofMTAM in many fields, such as medical, biotech, energy and . In the medicalfields, MTAM has been developed as a crucial component for in vivo anti-cancerdrug assay, and with further integration of PDX concept, to a unique, highlypractical personalized cancer treatment scheme. Supported with scientificpublication and patent applications, Prof. Chen is currently engaged in manyfronts, including clinical platform sensitivity/reliability, regulatory andoverall cost, to translate these results to the commercialization marketproduct for not only the R&D of cancer drugs, but more importantly, savinglife of many cancer patients.
内容摘要：Novel hollow fiber substrate of microtube arraymembranes (MTAMs) were prepared via co-axial electrospinning and featuredseveral structural characteristics, such as highly aligned, micron-scale indiameter, one-by-one connected array formation. It can befurther functionalized by rendering their tube wall nano-porous. Representing asubstrate platform, MTAMs have wide range of applications, covering frommedical, biotech, energy, and environmental. Efforts has been paid to exploretheir potential with exciting results demonstrated. Among them, an in vivoanti-cancer drug assay of hollow fiber assay (HFA) was investigated andbenchmarked with current leading product. Further extending of HFA applicationwas realized by the integrating with patient derived tumor graft forpersonalized cancer drug selection. Other applications, such as yeast immobilizationfor ethanol bioconversion, nerve tissue engineering and hydrogen storage andcarry device will be also discussed.